To compare the effects of letrozole (2.5 mg) and anastrozole (1 mg) meant for ovulation induction in clomiphene (CC)-resistant women with PCOS. Another study by Gregoriou and associates40 treated 29 men with infertility and low T/E ratios ( 10) and normal gonadotropin levels with either anastrozole or letrozole daily. They found an improvement in both hormonal and semen parameters after treatment with AIs. Has anyone used or are currently using Anastrozole to treat infertility? What is your opinion and/or experience. I used clomid for 5 months to treat low estrogen and progesterone levels, clomid did not help. Anastrozole single-dose protocol in women with oligo- or anovulatory infertility: results of a randomized phase II dose–response study Adjuvant Treatment. Anastrozole tablets are indicated for adjuvant treatment of postmenopausal women with hormone receptor-positive early breast cancer. To the Editor: I read with great interest the article by Tredway D et al. (1), in which they concluded that “in terms of ovulation rates, 5-day anastrozole at 1,5, and 10 mg/d was less effective than CC at 50mg/d for cycle 1”. Anastrozole and testolactone have similar effects on hormonal profiles and semen analysis. Anastrazole appears to be at least as effective as testolactone for treating men with abnormal testosterone-to-estradiol ratios, except for the subset with the Klinefelter syndrome, who appeared to be more effectively treated with testolactone. Easy-to-read patient leaflet for Anastrozole. Includes indications, proper use, special instructions, precautions, and possible side effects. Includes indications, proper use, special instructions, precautions, and possible side effects. Starting a family with a partner that you love is one of the most magical and exciting experiences that you will ever encounter. It is also daunting and very intimidating, but ultimately, becoming a parent will change you for the better. An expanded analysis of patients from this study compared 101 subfertile men treated with anastrozole vs. 74 treated with testolactone and demonstrated an improved T/E 2 ratio in both groups (12 x 12 Raman, J.D. and Schlegel, P.N. Aromatase inhibitors for male infertility.